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Updated Week 12 Defense Fantasy Rankings: D/ST lineup tips on who to start, best sleepers, streamers

The D/ST position in fantasy football is often overlooked. However, selecting the right defense can be the critical factor that determines victory or defeat each week. 

Never start an elite NFL defense in a poor matchup, as it may not always produce fantasy points for the D/ST position. The best approach is to focus entirely on matchups. 

Here are our Week 12 D/ST fantasy rankings, best starts, sleepers, and some matchups to avoid.

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Fantasy Football Defense Rankings Week 12: Who to start, sit at D/ST

📋 Week 12 Fantasy Rankings: QB | RB | WR | TE | D/ST | PK | ​​Flex Half-PPR Cheat Sheet

Updated 11/21:

Rk Team Defense OPP Rk Chg
1 Seattle Seahawks @TEN  
2 Baltimore Ravens NYJ ⬆️ 1
3 Detroit Lions NYG  
4 Green Bay Packers  MIN  
5 Cleveland Browns @LV  
6 New England Patriots @CIN ⬆️ 1
7 Chicago Bears PIT  
8 San Francisco 49ers CAR  
9 Carolina Panthers @SF  
10 Houston Texans BUF TNF
11 Buffalo Bills @HOU TNF
12 Los Angeles Rams  TB  
13 Atlanta Falcons @NO  
14 Tampa Bay Buccaneers @LAR ⬇️ 1
15 Arizona Cardinals JAX  
16 Kansas City Chiefs IND ⬆️ 1
17 Minnesota Vikings @GB  
18 New Orleans Saints ATL  
19 Pittsburgh Steelers  @CHI  
20 Jacksonville Jaguars  @ARI  
21 Las Vegas Raiders CLE ⬆️ 1
22 Tennessee Titans SEA  
23 Philadelphia Eagles @DAL  
24 Indianapolis Colts @KC  
25 New York Giants @DET  
26 Cincinnati Bengals NE  
27 New York Jets @BAL  
28 Dallas Cowboys PHI  
BYE Denver Broncos BYE  
BYE Los Angeles Chargers BYE  
BYE Miami Dolphins BYE  
BYE Washington Commanders BYE

 

Which D/STs have a bye in fantasy Week 12?

  • Denver Broncos
  • Los Angeles Chargers
  • Miami Dolphins
  • Washington Commanders

BEST PICKUPS: Week 12 waiver wire

Who are the best fantasy defenses in Week 12?

This week is full of targetable matchups at the D/ST position. You truly could not go wrong with any of the units in the top five of these rankings. 

Seattle has been outstanding for fantasy football this season, and it’s the best possible matchup with the Tennessee Titans—the Titans average just 14.4 points per game, the lowest in the NFL. 

Who are the best fantasy D/ST sleepers in Week 12?

The matchup between the Falcons and Saints is fascinating. Neither defense is that great, but the offenses are inconsistent at best. 

If this is a low-scoring game, both units could find opportunities for fantasy points. 

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