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Man United vs. Man City prediction, odds, betting tips and best bets for Premier League Manchester derby

The final Manchester derby of the 2024/25 season will have an air of desperation to it as both sides look to salvage disappointing seasons when they clash at Old Trafford on Sunday.

Manchester City have fallen from their English league mantle, simply struggling to stay afloat in the race for a Champions League place. They sit fifth on 48 points, occupying the final UCL qualifying spot, just one point above Newcastle and Brighton who are hot on their heels.

United, meanwhile, are in dire straits, sitting 13th with just 37 points through 30 games. They will largely be placing the most importance on their Europa League campaign, but this rivalry match will have plenty of meaning to them as well.

While the Red Devils have not been at the same level as their cross-town rivals in recent years based on accomplishments and finishing position, they have gone three unbeaten against City across three different competitions, and that alone will give them confidence of another result.

MORE: A complete guide to betting on soccer in the United States

Man United vs. Man City prediction, odds

  • Moneyline lean: Man City (+110 on DraftKings)
  • Score prediction: Man United 1-2 Man City

Manchester City have had a tough time recently in games against their arch-rivals, but they should get a return to winning ways in this derby.

The injury to Erling Haaland is obviously a blow, but City may benefit from giving opponents a different look up front. Omar Marmoush ran the show against relegation-threatened Leicester City midweek and looked sharp, and City have a number of players who look to be slowly improving under Pep Guardiola.

Meanwhile, Man United still look utterly lost under Ruben Amorim, and while their squad may be tightly knit, their quality is low in the end. They will have to grind out a result if they wish to get something out of this match.

  DraftKings
(USA)
Man United win +220
Draw +265
Man City win +110
Both teams
to score
Y: -195
N: +145
Over / Under
2.5 goals
O: -180
U: +120
Man City
-0.5 goals
+100
Man United
+0.5 goals
-145

Man United vs. Man City match facts

  • Date: Sunday, April 6, 2025
  • Kickoff Time: 4:30 p.m. local (11:30 a.m. ET / 7:30 a.m. PT)
  • Location: Old Trafford (Manchester, England)
  • Referee: John Brooks, VAR: Paul Tierney
  • Last meeting: Man City 1-2 Man United (Dec. 15, 2024 | Premier League)

 

MORE: Latest team news and injury updates ahead of Man City vs. Man United

Man United vs. Man City best bet

Man City are as inconsistent as they’ve ever been, but the addition of Omar Marmoush has been an unmitigated success. Since his arrival in January, he has logged 0.41 xG+xA per 90 minutes of Premier League action, with four goals to his name plus zero assists on 1.02 xA.

Now that Erling Haaland is out injured for the next month or more, Marmoush will take over up front and could provide an injection of energy at the No. 9 position. Not that Haaland was a problem — far from it — but City have been criticized for being one-dimensional with him at the helm.

Marmoush provides a different look and a uniquely talented one, able to combine with City’s wingers and other playmakers who are dangerous on the ball running at defenders. Expect him to have a major impact on the game, especially given he’s their main corner taker. United have been awful defending set pieces.

Man United vs. Man City prop bet

Manchester United have not eclipsed this mark for total shots against Manchester City in quite some time, but this matchup will be different than recent meetings for a number of reasons.

Man City have conceded the second-fewest shots in the Premier League this season, but since the start of 2025, that number is much softer. They’ve conceded 113 shots across 11 matches in that span, with five clubs below them in the list.

United, meanwhile, have taken the same amount of shots than City in that same span, ranking sixth in the Premier League for total shots. Under Ruben Amorim, the Red Devils have looked to have a pop on goal more often, even if those efforts are low-value opportunities. The chances have been poor, resulting in horrid efficiency — their 0.09 xG per shot in 2025 is third-worst in the league — but there’s been a clear emphasis on testing the goalkeeper regardless.

Expect United to have a go from anywhere on the pitch, especially if they’re chasing the game.

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